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Benzodiazapines and drug life cycles » Squiggles

Posted by Alan on November 6, 2002, at 18:46:16

In reply to Re: Withdrawal...AD's vs. bzds » Alan, posted by Squiggles on November 6, 2002, at 8:44:57

> Alan,
>
> I think "convinced at last" is meant to
> refer to "the protracted syndrome" debate by
> Hiba.

Yes, and I throughly addressed that in an earlier post.


> Regarding the comparison to benzos... I can't say really;
> certainly you do not hear of such rage, leading to
> murders, suicides, but there is rage enough to account
> for airplaine rage, and car rage, and possibly domestic
> rage; the thing with benzos, is that in cases of
> panic and agitation resulting from inter-dose withdrawal,
> there is the dubious advantage of being able to pop
> another pill. You can't do that with SSRIs.
>
> Squiggles
==========================================
Interdose withdrawals are demonstrative of having not kept steady state levels to begin with. Otherwise it's a case of simple mismangement or lack of understanding about the usage of the medication by the patient...not to mention longer half-life versions available to both physician and consumer alike. It is really no more complicated than that.

The key disadavantage about the AD's is that they work in a completely different way and work over the longer term. That is why many augment with bzds since the activating or agitating effect of being so stimulatd by AD's is in need of an antidote.

What's dubious is the acceptance by government agencies (the FDA comes to mind) of AD's for anxiety disorder in the first place with the co's admitted test results in the 30 - 50% efficacy range and bzds far, far above that.

There is a life cycle for newly introduced drugs (or many new products) that the ssri's are beginning to see whiplash from overprescription now just like valium suffered from in the late 60's and early 70's.

Unfortunately, it's not the patients that never recovered from the overuse and overprescriptions of these drugs...quite the contrary. Far more damaging are the lingering misperceptions and pure stigmatising baloney still seized on by the anti-bzd movment...that which unnecessarily scares off potential candidates for bzd therapy due to these misperceptions.

Alan


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URL: http://www.dr-bob.org/babble/20021101/msgs/126709.html