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Re: Just another SSRI *again*

Posted by JLM on November 7, 2002, at 4:57:41

In reply to Re: Just another SSRI *again* (nm), posted by Maximus on November 4, 2002, at 20:13:39

This drug was abandoned by Lilly. It was found to cause cardiac QT abnormalities.

Wanna hear something interesting thou? Lilly claimed in their patent that r-fluoxetine reduces the serious side effects of Prozac that Lilly claims DO NOT EXIST. They have vehemently denied them in numerous court cases.

http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=/netahtml/search-bool.html&r=8&f=G&l=50&co1=AND&d=ft00&s1=r-fluoxetine&OS=r-fluoxetine&RS=r-fluoxetine

From the US Patent Office:

"Pure R(-) fluoxetine functions as an effective antidepressant with a shorter half life and shorter duration of action than the racemic mixture or the S(+) isomer of fluoxetine. Having a shorter half life and shorter duration of action results in less accumulation of R(-) fluoxetine in a patient's body. This in turn results in decreased adverse effects including headaches, nervousness, anxiety, insomnia, inner restlessness (akathisia), nausea, diarrhea, drowsiness, decreased libido and/or sexual dysfunction, suicidal thoughts and self mutilation."

Suicidal thoughts? Akathesia? Time and time again Lilly has denied in court that the original Prozac causes these types of adverse events, and yet they claim that their new version of the drug does NOT cause them. Does this make a damn bit of sense to anyone?

Its also HIGHLY interesting to note that one of the inventors of the drug is Martin Teicher, who wrote several papers on SSRI induced suicidality, something that Lilly has denied time and time again. In fact when he first brought it up, Lilly tried to discredit him. But later they pay 80 million for a drug that he helped developed.

My conclusion for this is that the Eli Lilly management/legal department is suffering from a severe delusional disorder and should seek treatment immediately. GRIN. But seriously, you really have to wonder. Martin Teicher's credits are IMPECABLE. So are JD Cole's, his coauthor of the suicidality studies. JD Cole I believe was once president of the American Academy of Neuropsychopharmacology.


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poster:JLM thread:126251
URL: http://www.dr-bob.org/babble/20021101/msgs/126777.html