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Re: Antipsychotics » Kari

Posted by Dinah on November 19, 2002, at 15:03:38

In reply to Re: How much do you take? -- » oracle, posted by Kari on November 19, 2002, at 13:53:48

Kari, I can find almost nothing on how antipsychotics work, other than that they don't know. I realize they work on D2 receptors, but that doesn't really explain it in terms of functioning. Is it that excess dopamine causes overstimulation? And what the drug does is to reduce overstimulation?

How does dopamine work in both Parkinsons and Schizophrenia? Do the side effects of antipsychotics mimic Parkinsons? Or is it a different dopamine receptor involved in each. I'm reading Awakenings right now, but haven't found any answers to my befuddlement.

Risperdal worked great on me in a way, but there was almost an on/off switch in terms of emotions. My pdoc said that would wear off, but for me to believe him I have to be able to understand how it works.

I know I'm inundating you with questions, and I certainly don't expect you to know the answers. I can't even find where the scientists know the answers. After having been on SSRI's for a while, I have a pretty good idea of the way they work, at least in me, altho I hear other people have different experiences. Why can't the scientists explain these things better? Or is my lack of Google ability showing again.

 

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poster:Dinah thread:128002
URL: http://www.dr-bob.org/babble/20021116/msgs/128328.html