Posted by polarbear206 on November 24, 2002, at 8:32:45
In reply to Any Desipramine veterans?, posted by rytoor on November 22, 2002, at 12:49:20
> Any Desipramine veterans out there? Success stories or otherwise?
>
> I recently started a trial of Desipramine. I'm trying to get up to a therapeutic dose, and have hit 100 mg as of Day 12. I know I’m probably only half way to a therapeutic dose.
>
> But the side effects are tough to take. Do they go away? Or diminish?
>
> So far, side effects include: weight gain (must be water, since diet hasn’t changed and is pretty healthy); complete spaciness and fatigue, especially when taking more than 25 mg at a time; cold hands (of all things!!).
>
> If I can’t handle higher doses, and so far it doesn’t look good, my next option for a NE-targeted AD is Reboxetine. Effexor has failed several times, again because I can’t get up to the mega doses.
>
> I’m also on Lexapro and Dexedrine. Please share,
>
> R
>R,
The desipramine will increase your lexapro blood levels. Could be why your are having more side effects. I used to take paxil and imipramine together. This happened to me when I added the imipramine. You have to wein down on a tricyclic to avoid the flu-like effects of going off of them too abruptly.
Laura.
poster:polarbear206
thread:128780
URL: http://www.dr-bob.org/babble/20021122/msgs/129028.html