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Re: Effexor XR - Alternatives? » khead

Posted by jimmygold70 on December 25, 2002, at 11:07:33

In reply to Re: Effexor XR - Alternatives? » jimmygold70, posted by khead on December 22, 2002, at 8:36:40

Generally speaking, I would not mix trazodone with venlafaxine (Effexor). Both drugs are reuptake inhibitors of the same monoamines (Serotonin and Dopamine). The interaction is mostly leading to more side effects, and I suggest high BP is one of them. Maybe taking Remeron instead of all will provide you with a better side effects profile - a selective serotonin and noradrenaline AD (not a reuptake inhibitor). Serzone is actually a good option as well, a mechanism similar to Trazodone, improves sleep and less likely to cause side effects related to most ADs (Journal of Clinical Psychiatry, Feb 2002, Supplement - Focus on nefazodone)

Good luck!
Jimmy

> > It's generally a good med. What do you feel while taking it?
> >
> > Jimmy
>
> So far so good at week 4. (With the exception of
> elevated blood pressure which was pretty high
> to begin with. Reduced the dose from 150 back to 75 which seems to have helped. Will be discussing the BP situation with my Doc this week.) I'm also on Trazodone 150 at bedtime which definately helps in the sleep department. Perhaps somewhat more "jittery" than usual, but then again I'm also a "jittery" type to begin with. The good news is that I'm now MUCH better able to handle my anx/depress. It's not gone by a long shot and given my current circumstances as well as history I really do not, and did not, expect magic. To me, ANY relief from misery is a good thing.


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