Posted by BrittPark on January 19, 2003, at 16:57:45
In reply to Older drugs vs. newer drugs..., posted by jay on January 19, 2003, at 16:08:22
I've found imipramine to be generally effective for the last 20 years and have found the side-effects, dry mouth and a tendency to become constipated, to be perfectly tolerable. My one trial of an SSRI (Paxil) didn't do much and made me jittery and slightly nauseated. All in all I prefer the TCAs to the SSRIs.
I think there is clinical evidence that third generation ADs are slightly better tolerated than TCAs, but the difference is small. I think doctors prescribe SSRIs in preference to TCAs not so much because SSRIs are more effective (they're not), or because they have more tolerable side effects, but because they are safer in overdose. There might also be a bit of "Marketing" at work ;)
Cheers,
Britt
poster:BrittPark
thread:136591
URL: http://www.dr-bob.org/babble/20030119/msgs/136593.html