Posted by Ame Sans Vie on January 20, 2003, at 1:56:19
In reply to Re: What's Best? » Ame Sans Vie, posted by hildi on January 19, 2003, at 20:12:47
First, yes, adrafanil is sort of considered the "unrefined" version of modafinil. But unlike other stimulants, Provigil has a very unique modus operandi. I.E., while amphetamines exert their action primarily through release/reuptake inhibition of dopamine and noradrenaline, modafinil seems to have very little or no effect on dopamine, and surely none on noradrenaline. It works by activating the parasympathetic part of your hypothalamus; the *sympathetic* hypothalamus, if stimulated, would cause excessive anxiety-- the "fight or flight" response. The parasympathetic area is largely not understood, though. The only practical information I can offer at this point is that I have yet to hear of a single person experiencing *any* side effects from Provigil. It helps to think of it as what it really is-- a wakefulness-promoting agent, even a mild euphoric at higher doses, but not a stimulant in the classic sense of the word. Even still, since beginning this drug I have been able to very easily skip my morning coffee, and because of this my GERD is now completely nonexistant. :-)
Yes, I was the one who didn't respond to Neurontin, but I was on a very low dose. I would like to try it again at a much higher dosage.
And I'm sure you've gathered this already from my other posts by now, but I take Valium, Klonopin, Xanax, and Ativan.
--Michael
poster:Ame Sans Vie
thread:136539
URL: http://www.dr-bob.org/babble/20030119/msgs/136689.html