Posted by david maclean on February 20, 2003, at 9:32:09
In reply to Re: Near the end: What meds can I try? Quick pls! » david maclean, posted by likelife on February 20, 2003, at 0:02:05
> Funny how there's so much conflicting info. out there.
>
> I got the info. from PDR Drug Guide for Mental Health Professionals, under Section 2: Interactions with psychotropic drugs. Under methylphenidate (generic for Ritalin) is listed moclobemide: Concurrent use of methylphenidate and moclobemide may result in hypertensive crisis (headache, palpitation, neck stiffness). The onset is rated as 1, rapid (develops within 24 hours). Severity is 1, contraindicated (the interaction may be life-threatening; concomitant use of the interacting agents is contraindicated). The evidence for this is a 3, fair (available documentation is fair, but pharmacologic considerations lead clinicians to suspect the interaction exists; or, documentation is good for a pharmacologically similar drug).
>
> Hope that helps,
>
> Natalie
>
Natalie, you are an absoulte star for providing me with that info. Thank you very much indeed! It is much appreciated especially as I intend to pursue the Ritalin for my dysthymia.Maybe the real worry in what you have quoted is not of an interaction per se between moclobemide and Ritalin. But rather than one does something similar to the other and the result may (or may not) be an excess dose of stimulant.
Now I must puzzle over why such a clear warning as the one you have quoted is unknown to the person I spoke to at Roche here in the UK (at a conversational level, at least). I think they are probably not as well informed as they should be. To be fair, they did say that my doc or pharmacist should contact them to get a proper search done ... but if it is in black and white in the US specs then I would have thought they would have known of the warning.
I think I will now go and visit my pharmacist to see if he has info in his drug ref book.
Thank you once again.
Dave
poster:david maclean
thread:200976
URL: http://www.dr-bob.org/babble/20030219/msgs/202135.html