Posted by Ritch on April 10, 2003, at 13:51:57
In reply to Re: Abilify and insomnia, posted by lapdog on April 10, 2003, at 0:35:31
> Thank you both for your responses - obviously insomnia is a problem, more so for some than for others.
>
> I have another question. Do you suppose that it is possible for the manufacturer to break down Abilify into two medications? One components seems especially helpful in regard to cognitive slowing, communication, and clear thought processes. The other component seems to energize and control depression. I wish we could the ratio of one to the other.
>
> I often have the impression that the manufacturers of Geodon and Abilify (and other major anti-psychotics) are trying the capture the market with an all-in-one knockout drug. Not understanding the neurochemistry involved, I cannot validate or invalidate this. What do you think?
>
I think you are very correct in your assertion. Abilify hits more receptors than Remeron (and I thought that was a bunch). Abilify has moderate affinity for the serotonin transporter, so in a way you are taking an SRI and that may be why there are many complaining of insomnia while on it (also the half-life is lengthy). Abilify will probably be the biggest competitor to Lilly's new combo of Prozac+Zyprexa.
poster:Ritch
thread:217636
URL: http://www.dr-bob.org/babble/20030407/msgs/218244.html