Posted by Ame Sans Vie on April 11, 2003, at 19:41:39
http://www.orphan.com/ArticleDetail.cfm?ID=371
"During 2003, the Company expects to begin a proof-of-principle study to evaluate Xyrem for symptomatic treatment of Fibromyalgia Syndrome (FMS), a chronic condition that is estimated to affect as many as six million individuals in the United States. Fibromyalgia Syndrome is characterized by widespread pain in joints, muscles, tendons, and other soft tissues. Other symptoms include persistent fatigue, headaches, cognitive or memory impairment, morning stiffness and non-restorative sleep. The cause of fibromyalgia is unknown, although an imbalance in growth hormone production may play a role. Studies have demonstrated improvement in symptoms in FMS patients given growth hormone. In addition to increasing restorative sleep, Xyrem may be a growth hormone secretogogue and may therefore produce symptomatic relief. The Company does not expect results from this proof-of-principle FMS study until the second half of 2004."
Maybe I can get rid of this horrible Elavil and begin using Xyrem for more restorative sleep. Though, I have to wonder, even since I first started taking Elavil for restorative sleep, I haven't noticed any of the symptoms of FMS/CFS diminish. Except of course when I pop Flexeril and Soma all day (not complaining about that though, lol). But I digress...
Also of interest:
"Orphan Medical stated that it has begun development of a new patent-protected formulation of Xyrem. The Company is evaluating formulation alternatives that could extend the activity of a single Xyrem dose from the current two-four hour range to a six-eight hour range."
Now this makes a little more sense to me... I mean, how could a person get a totally restorative sleep if they have to set their alarm to wake up in the middle of the night for their next dose?
poster:Ame Sans Vie
thread:218632
URL: http://www.dr-bob.org/babble/20030411/msgs/218632.html