Posted by jemma on April 13, 2003, at 13:23:35
In reply to Re: Serious side effect reported, posted by Larry Hoover on April 11, 2003, at 22:46:37
> > I'm sorry if this is a repeat; I didn't read any of the other threads under here, but thought I would comment that a pdoc told me that the WEIGHT GAIN people have from ZYPREXA has resulted in it being a possible cause of usually adult-onset diabetes. G-d knows what the weight gain would do to children.
>
> I feel pedantic to point this out, but the relationship between weight gain and diabetes is correlative, not causative. For all we know, the trend towards diabetes might cause weight gain, or both may be symptoms of a separate pathological process. Symbolically, a correlation between A and B could be explained by: A leads to B, B leads to A, both A and B are caused by C, or a statistical coincidence. The doctor who spoke to you should know better.
>
> Frankly, it looks very much like both the weight gain and the diabetes are caused by Zyprexa, but that is just my educated *guess*.
>
> Lar
>
Hi Larry -As always, I appreciate your careful science and refusal to leap to conclusions from inconclusive data. But I have always suspected that the prime mechanism for med-related weight gain is insulin resistance, and these findings seem to support that. I have also read of good success in preventing and reversing weight gain with the co-administering of glucophage (metformin) along with ads and aps.
- jemma
poster:jemma
thread:218530
URL: http://www.dr-bob.org/babble/20030411/msgs/219010.html