Posted by Questionmark on April 30, 2003, at 20:52:49
In reply to Why Dirty Drug » SLS, posted by jack smith on April 30, 2003, at 17:01:40
> "Scott, or others, why are TCA's and MAOI's referred to as dirty drugs? I have never quite understood this. Is it just because they are not selective. Or is it because of the TCA's anticholinergic (sp?) effect? Just wondering."
i've really only heard this in reference to TCAs. But yeah, it always seemed like it was referring to their strong anticholinergic and "anticognitive" effects. i think.
Ace, on the REM thing-- yeah many antidepressants are known to reduce the frequency and duration of REM sleep (and the rebound upon discontinuation). i've actually read that this is especially true with Nardil. So in regard to this Anafranil should be no worse. (i wish i knew what to tell you to do. but i can't even decide for myself). Good luck.
>"This is true; this is why TCAs are given for bed-wetting. I've not heard of SSRIs given for this condition."
Actually TCAs are probably given for bed-wetting because of their anticholinergic effect of , well, making it harder to urinate basically, and not because of their effects on sleep architecture.
poster:Questionmark
thread:223044
URL: http://www.dr-bob.org/babble/20030429/msgs/223533.html