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Re: Thank-you Scott... » lillabelle

Posted by SLS on May 27, 2003, at 7:06:56

In reply to Thank-you Scott..., posted by lillabelle on May 27, 2003, at 3:24:33

> Are strattera and phentermine at all similar? Have you tried strattera? Thanks again and look forward to replies.

Hi again.

I would say that the two are dissimilar. Although they both affect the neurotransmitter norepinephrine NE, they do so in different ways. Phentermine increases the amount of NE released by the first neuron into the synapse (the gap separating the first and second neurons). In this regard, it is similar to Dexedrine or Adderall. Strattera increases the amount of NE in the synapse by preventing the first neuron from recapturing it once it has been released. In this regard, it is similar to many antidepressants. I am considering using Strattera for any antidepressant properties it may have. Although seemingly different from the classical stimulants, Strattera has shown itself to be effective in treating ADD/ADHD. I don't have ADD/ADHD, but I have seen plenty of people here report using it successfully. I am impressed that Strattera can improve both attentional deficits and behavioral and hyperkinetic disturbances. Strattera was originally investigated for depression under the name tomoxetine, although I don't know how effective it was shown to be. Perhaps it would be helpful when treating comorbid (occurring at the same time) ADD/ADHD and depression. I wish I had a more definitive recommendation for you.


- Scott

 

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