Posted by Ame Sans Vie on June 19, 2003, at 9:16:50
In reply to Ames, Re: Mirapex ('Mirapexin' in the UK), posted by McPac on June 19, 2003, at 2:42:10
> Does Mirapex do anything for OCD?
> Any studies saying so?
> Thanks!
Hi McPac,Sorry, but all the studies I've read regarding dopamine, dopamine agonists, and OCD suggest that dopamine-agonism is something you definitely want to avoid, unless your OCD is accompanied by tics. If I understand correctly, the main reason for this is that, in most OCD patients, norepinephrine levels are too high. SSRIs not only regulate serotonin, but also balance out the NE. However, dopamine turns into norepinephrine in the brain, so using a dopamine agonist would probably be a bad idea, unless it was at a low dose (maybe up to 0.25mg Mirapex three times a day).
All the research I came across suggested using dopamine *antagonists* (anti-psychotics) when necessary as adjuncts to primary OCD meds.
poster:Ame Sans Vie
thread:233583
URL: http://www.dr-bob.org/babble/20030619/msgs/235038.html