Posted by matthhhh on July 18, 2003, at 18:21:17
There are several studies that indicate that morphine provides relief from ocd taken orally only once a week! Studies indicate that it acts on the caudate nucleus which the area of the brain that is implicated with ocd.Check out this info.
Exciting evidence recently published in the Canadian Journal of Psychiatry suggested morphine as an efficacious drug that showed dramatic effects in cases in which SSRI's, behavior therapy, and psychosurgery failed (Warnecke 1997). The author referenced several imaging studies showing a concentration of opioid receptors in the caudate nucleus, an aforementioned important region in the pathogenesis of OCD (Murin et al. 1980; Woo et al. 1985). Notably, none of the patients reported a euphoric response after each dose of morphine, which suggests that the mu subclass of opioid receptors may not be involved and the risk of addiction should be very low. Oral doses of morphine were given with doses ranging from 20 to 40 mg. Surprisingly, therapeutic effects lasted for at least 5 days following a single dose.
Does anyone have any experience with morphine for ocd?
I can see why this can be true, b/c I recently recieved morphine when I had my wisdom teeth taken out. For several days I had complete relief from my ocd and social phobia.
poster:matthhhh
thread:243298
URL: http://www.dr-bob.org/babble/20030718/msgs/243298.html