Posted by Larry Hoover on August 3, 2003, at 10:44:56
In reply to Re: stimulants: tyrosine, phenylalanine, dexedrine » Larry Hoover, posted by Rickson Gracie on August 3, 2003, at 10:02:32
> Mr Larry,
> You seem well versed on things....Do you know anything about Selegiline? The products you mention are supposed to enhance the effects.Just curious if you knew about Selegiline?Selegiline is an irreversible inhibitor of monoamine oxidase B, the form of MAO found mostly in the brain. By blocking MAO-B, selegeline will increase the effectiveness of "normal" release of neurotransmitters, by reducing the rate at which they are destroyed. That goes for dopamine, norepinephrine, serotonin, and others.
Selegiline also is believed to selectively inhibit dopamine reuptake, similar to how SSRIs inhibit serotonin reuptake.
Also, two of the metabolites of selegiline are amphetamine and methamphetamin, which have obvious stimulatory activity.
Taking precursors of dopamine (tyrosine or phenylalanine) increases the supply of dopamine. Taking selegiline keeps the supply of dopamine from being destroyed as quickly as it would otherwise be. So, yes, taking dopamine precursors would enhance the effect of selegiline.
Lar
poster:Larry Hoover
thread:246486
URL: http://www.dr-bob.org/babble/20030802/msgs/247742.html