Posted by Ofan on August 7, 2003, at 3:21:51
Greetings, all.
I'm hoping someone more biochemically literate than I am can shed some light on a nagging question...
I have recently started on Wellbutrin (I am concurrently taking Celexa for OCD, but it isn't doing enough for the depression I'm also experiencing.) One difficulty I have with switching or adding medications (and staying on them once switched) is a fear of drug toxicity.
As is usual, I researched the drug as thoroughly as my limited knowledge of neurobiology allows. I discovered that bupropion is chemically rather similar to diethylpropion, a drug apparently used to treat obesity. Further research yielded
several journal abstracts indicating a level of neurotoxicity associated with diethylpropion, related to oxidative stress and excitotoxicity.So here's the question: Given the chemical similarity between bupropion and diethylpropion, is it possible that bupropion might exhibit
neurotoxicity as well?Anyone have any thoughts on this?
poster:Ofan
thread:248841
URL: http://www.dr-bob.org/babble/20030802/msgs/248841.html