Posted by linkadge on August 29, 2003, at 15:00:56
In reply to Need some SSRI with your Effexor?, posted by Bill L on August 29, 2003, at 12:07:07
I think the problem is that we don't have the correct combination of serotonin and norepineprine in our antidepressants.
Even though Effexor has somewhat lesser effects on Serotonin than on norepinephrine, I still beleive its norephiniephrine effect is too strong. Many find it too stimulating, thats why they switch to a SSRI.
But SSRI's on the other hand can sometimes cause apathy because of norephinephrine downregulation.
This is perhaps why a combination of the two has proved to be so useful. Because you can boost the serotonin effect and still retain some norepinephrine effect.
Linkadge
poster:linkadge
thread:255321
URL: http://www.dr-bob.org/babble/20030828/msgs/255362.html