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Re: I thought people lost weight on Parnate?

Posted by Caleb462 on September 16, 2003, at 23:31:09

In reply to Re: I thought people lost weight on Parnate? » loolot » cubbybear, posted by Ame Sans Vie on September 16, 2003, at 17:30:23

> I think I've brought this up here once before -- I think the few people who gain weight on speed do so because rather than forget about eating altogether, they just eat really fast. :-) Though it's still debated whether Parnate is actually metabolized to amphetamine and methamphetamine as has been suggested before, something in it certainly causes a release of norepinephrine into the brain that's quite amphetamine-like. And there is at least one case report of a serious Parnate addiction. I don't mean dependency, I mean *addiction*. Like some woman was taking 400-500mg/day to keep the amphetamines in her system:
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1873639&dopt=Abstract

My assumption is that parnate, due to it's relation to amphetamine, has the ability to induce norepinephrine/dopamine release. The amphetamine/methamphetamine metabolite theory has pretty much been proved false.


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