Posted by Kacy on September 20, 2003, at 8:11:52
In reply to Re: Strattera and fatigue... patience, posted by ready for change on September 18, 2003, at 13:01:22
My doctor won't augment Strattera with a stimulant and insisted on evening dosing to get rid of the afternoon sedation that just won't end. He believes that eliminates the problem and anything else is all in my head. Well, it did end the problem, but it also eliminated the Strattera. With evening dosing, I don't get any effect during the day.
The drug doesn't last 24 hours at a therapeutic level for me. It lasts about 10 hours. The decline in the evening is easy to track by the return of anxiety. It keeps increasing from late afternoon on. The best thing Strattera has done for me has been to take that away. I don't think I realized how much anxiety I had and how much I must have always had until I began Strattera. Taking away anxiety, alone, helps some with add/inattentive problems. The kicker is killing me, though. I just went back to am dosing and the afternoon sedation is back full force.
I understood more when I saw that the drug's half-life was 5.15 hours. But, that is about the same half-life as Effexor. So, why would Effexor last 24 hours a day while Strattera lasts ten?
Do the rest of you who take it in the evening get the benefit of the drug during the day? Does anyone else experience what I do?
poster:Kacy
thread:133458
URL: http://www.dr-bob.org/babble/20030917/msgs/261894.html