Posted by lil' jimi on September 23, 2003, at 1:18:12
In reply to re: MAOI and Ecstacy, posted by pontiacfiero69 on September 22, 2003, at 23:35:09
> > i don't know, but this part sounded bad ... ...
> >
> > " These data suggest that the deamination by monoamine oxidase-B of excessive dopamine within the 5-HT terminal generates hydrogen peroxide that may lead to membrane lipid peroxidation, and perhaps other oxidative insults, resulting in selective 5-HT terminal degeneration subsequent to MDMA treatment. "
> >
> > ... sounds like that could hurt
>
> Yes it does. However, if I understand the abstract correctly, the observed neurotoxicity and serotonin terminal degeneration appeared to be blocked by l-deprenyl.
>i appreciate the assist there ...
... let me try that again ... ...
... i think you're going to have to give me some more help here ...
... i've read it 4 times just now ...
... it's like i'm having to diagram these sentences ...
... or working a math problem
... one where you solve the equation for 'x'
... ... (HA!)
... (sorry)... anyway
... here's where i got (get) lost ...
isn't the
monoamine oxidase-B
(this is the MAOI, right ?)
... the same as l-deprenyl ?... fifth time and now i know the answer is yes ...
... still sounds to me like the maoi decreases some bad things from the x "treatment" of the rats ... only to contribute to some really bad things in that last sentence there ...
... isn't the l-deprenyl's deanimating the excess serotonin from the mdma treatment ... causing this H2O2 to burn out the 5HT terminals ?
... IF i was right about that, wouldn't it be better to just let the x do it's worst and leave worse enough alone ?
poster:lil' jimi
thread:228754
URL: http://www.dr-bob.org/babble/20030917/msgs/262579.html