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Re: SSRIs vs. SNRIs

Posted by SLS on October 22, 2003, at 2:42:36

In reply to Re: SSRIs vs. SNRIs, posted by ace on October 22, 2003, at 0:18:13

Hi.

There always seems to be some confusion regarding the acronym "SNRI". There doesn't seem to be a universal convention among authors. Depending on who you read, SNRI can stand for either "serotonin / norepinephrine reuptake inhibitor" or "selective norepinephrine reuptake inhibitor". To make things even more confusing, the acronym "NARI" is often used to mean "noradrenaline reuptake inhibitor".

Remeron is not a reuptake inhibitor of either norepinephrine nor serotonin. It acts to block neurotransmitter receptors. It acts as an antagonist of:

norepinephrine NE alpha-2 receptors (presynaptic)
serotonin 5-HT2 receptors
serotonin 5-HT3 receptors
histamine H1 receptors


- Scott

 

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URL: http://www.dr-bob.org/babble/20031021/msgs/271739.html