Posted by Pharmer Boy on November 4, 2003, at 0:38:58
In reply to Re: dysthymia and anxiety overwelming, posted by Rvanson on November 3, 2003, at 1:18:04
> > I have been reading a lot about amineptine and tianeptine lately. I have been diagnosed with dysthymia, generalized anxiety disorder also AD/HD (no physical hyperactivity), and found that the only pharm that ever helped me with the depression and anxiety was imipramine, but this was about 3 years ago. Since amineptine and tianeptine are also TCAs, they may do just as well, or better than imipramine. My depression is back with a vengance, and my anxiety is so bad I have severe back and stomach pain. Is anyone taking either one of these drugs with similar diagnosis? How well is it working for you? If both have been tried with success, which is most effective?
> > I appreciate any feedback. I want to get these horrible disfunctions under control, my personal and professional lives are suffering greatly.
>
> Amineptine and Tianeptine are not TCAs and they are not FDA approved. Not playing "doctor" here, just pointing out the facts.
>
> You can stiil get Tianeptine from offshore sources, but Amineptine is not made anywhere in the western world that I am aware of, due to a generlaized ban on its manufacture.
>
> Why not try the Imipramine again?
>
> Its cheap and legitamate in the US, if that is where you live.
>
> Just some thoughts. I hope you can find a good med and feel better soon.Amineptine is a TCA,(check out http://amineptine.com -and read the amineptine pharmacology link) also, tianeptine is a modified tricyclic (same base structure, just with extras tacked on). Any way the imipramine has too strong of an anticholinergic effect, I want to feel happier without feeling dumber- it killed my short term memory, and made me spacey. Additionally I have suspicions that my depression is linked more to a catecholamine cause than a 5HT cause from previous SSRI experiances, which is why I have interest in the more dopaminergic antidepressants.
The FDA doesn't approve of many drugs which are far superior to approved ones...maybe because the US Pharmaceutical companies can't profit from them, and cheaper versions are available overseas...so the FDA doesn't get any "funding" kicked to it by the Pharmaceutical companies if they were to approve use of those drugs.
poster:Pharmer Boy
thread:275952
URL: http://www.dr-bob.org/babble/20031030/msgs/276358.html