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Effexor, smoking and Dopamine depletion

Posted by socialdeviantjeff on December 1, 2003, at 19:31:45

Here's the thing...
I read somewhere that Effexor suppresses or depletes Dopamine. The depletion of dopamine is dependent on dose; more Effexor, less dopamine in the brain. Less effexor, more Dopamine in the brain.

What I'm wondering is how smoking factors into that. Nicotine cause a surge of Dopamine that lasts for a short while. While Effexor is having an action that increases the levels of Norepinephrine and Seritonon, it is also pulling down Dopamine. Would this explain why since I've started taking effexor I've also dramatically increased my smoking, been more irate, and still very depressed?

FYI, Im also using Tegretol. I think that it contributes my reduced level of anxiety and moderate adhenia.

I could be way off here, any opinions or suggestions are welcomed and appreciated.


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poster:socialdeviantjeff thread:285689
URL: http://www.dr-bob.org/babble/20031126/msgs/285689.html