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Re: Anger and Medication

Posted by Interject79 on December 15, 2003, at 14:53:00

In reply to Re: Anger and Medication, posted by moose100 on December 15, 2003, at 10:26:58

As a clarification, though this is counterintuitive serotonin acts as a post-synaptic excitatory neurotransmitter (in that it excites neural activity). On mood, it tends to inhibit aggressive behaviors in depressed individuals.

SSRIs can be helpful for mood disorders in some cases, if the cause is mostly a lack of serotonin. Mania or hypomania, also associated with irritability, is often made worse by SSRIs. Stabilizers sometimes do the trick here, boosting GABA, a distinctly inhibitive neurotransmitter.

My mood is made worse by SSRIs except Lexapro at a low dose. But it's also made worse by mood stabilizers, implicating a problem with dopamine production/uptake. Neuroscience is notoriously full of surprises.

Best,
interject


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poster:Interject79 thread:289834
URL: http://www.dr-bob.org/babble/20031213/msgs/290112.html