Posted by dreaman on December 24, 2003, at 14:41:24
In reply to ADD-inattentive - Adderall no longer helps - what , posted by btnd on December 20, 2003, at 14:57:27
Just to let you know I have had what seems like the exact same experience as your son with stimulants. I have inattentive ADD and was on Ritalin for about 1 year with amazing results till I started to become totally tolerant to it. Upping the dosage really did not seem to help. I switched to adderal and it had no effect either. Also I think the ritalin might have caused some of my depression and anxiety which I really never had before ritalin! I think inattentives might have this tolerance problem alot more often than hyperactive ADDers.
If someone could try to explain the neurochemistry of dopamine, ritalin, or cocaine tolerance I would be very interested to understand it! How does memantine work against this? Could ritalin cause a perminant down regulation for the Dopamine receptors in the brain?
I have decided to try Strattera. Today I will take my first pill 10mg pill. Anyway strattera might be a good next step in trying to conquer your sons ADD, as I have not heard much about tolerance. There is another post <Strattera for inattentive ADD ?> farther down. This tells about ADD effects of Strattera.
If you find something that really does block the effects of adderall or ritaln tolerance, let me know. Memantine sounds like it might help
poster:dreaman
thread:291940
URL: http://www.dr-bob.org/babble/20031219/msgs/293153.html