Posted by paulk on December 26, 2003, at 23:34:46
In reply to Re: MAO vs Adderall w/ Effexor, posted by kellym on December 26, 2003, at 21:00:41
I should probably have said that they are not as prone to poop out probably because the higher levels of transmitter are only near the neurons that are firing. (as it is I'm here because Nardil appears to have quite working for me after several years).
The MAOIs are not for everyone, but for dysthemia (AKA chronic depression or atypical depression – the most common form of affective disorder) I think the very old MAOIs are probably the best drug available. Having tried a number of other drugs, the only other one that helped was Effexor – but it only helped for 6 – 8 weeks. I have gotten good help from Nardil for some years instead of weeks and I think there may have been some therapeutic (curative) help rather than just symptomatic help.
My current understanding is that using any of these meds will over the long term cause a desensitization of the receptors – which can stop the beginning of vicious cycles. My problem is that the desensitization of seritonergic receptors was probably paired with other receptors that may now be under sensitive.
poster:paulk
thread:292067
URL: http://www.dr-bob.org/babble/20031225/msgs/293661.html