Re: ZOLOFT - Dopamine??? » SLS

Posted by rod on January 1, 2004, at 11:06:07

In reply to ZOLOFT - Dopamine???, posted by SLS on January 1, 2004, at 10:01:18

> How potent is Zoloft as a dopamine reuptake inhibitor? Compared to Effexor?
>
> Thanks again.
>
>
> - Scott
Im not sure...
look at the figure at http://www.preskorn.com/columns/9911.html
If I read it right, both Sertraline and Venlafaxine have an aprox. 100 fold increased affinity of Serotonin pumps vs. Dopamin pumps.
But my doctor told me that the net-effect of Sertraline overweights the effect of the blockade of the dopamine re-uptake pumps. And the net-effect of sertraline is increased *noradrenaline*, he said. I guess over some 5-ht receptors...
thats all I know
good luck with it!
Roland

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ZOLOFT - Dopamine??? SLS 1/1/04
Re: ZOLOFT - Dopamine??? » SLS rod 1/1/04
Re: ZOLOFT - Dopamine??? scott-d-o 1/1/04
Re: ZOLOFT - Dopamine??? zeugma 1/1/04

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