Posted by zeugma on January 5, 2004, at 3:09:03
In reply to Meridia as anti-depressant, posted by ethel basset on January 4, 2004, at 20:27:27
Here's some info on Meridia that you might find interesting:
http://www.psychotropical.com/notes/850.htmlI know that a company is trying to develop a metabolite of Meridia that is a triple reuptake inhibitor: dopamine, serotonin, and norepinephrine. Logically that would be a VERY powerful antidepressant.
There are other anomalies within the AD field, like the fact that LUvox is only approved for OCD in the US, when logically if serotinin reuptake inhibition is resposible for AD effect it should be just as good for depression as Prozac; or Strattera, which is similar in pharmacology to desipramine, one of the most widely-studied and attested antidepressant drugs, but which supposedly failed when tested as an AD over a decade ago. Again, this is a paradox if norepinephrine reuptake inhibition is truly desipramine's mechanism of action. Personally, I find Strattera to have a strong antidepressant effect, regardless of its official indication.
poster:zeugma
thread:296485
URL: http://www.dr-bob.org/babble/20031231/msgs/296594.html