Posted by rod on January 30, 2004, at 16:39:10
In reply to Re: IfTransdermal Selegiline is approved Sunday..., posted by bipolarspectrum on January 30, 2004, at 16:11:15
> > hmm, very interesting article Chairman_MAO.
> > But I have a question. Whats the deal with the transdermal selegiline? I mean ordinary selegiline is available for years and off patent, as far as i know. Is the transdermal form any better than the oral one? Or is it just a patentable form of selegiline? What about a extended release form of selegiline? Wouldnt that also work the same way?
> >
> > thanks
> >
> > Roland
>
> Roland,
> Transdermal selegiline has been claimed by many to possibly be a new 'first-line' treatment for depression, ie. the first thing physicians may prescribe for depression... The transdermal has HUGE advantages over the oral form, such as NO dietary restrictions and significiant reducions in metabolite formation... An extended oral selegiline would have the same problems as regular oral selegiline: amphetamine production and dietary restrictions.. in conclusion, in my opinion, transdermal selegiline, if approved, may improve the lives of countless depression sufferers..
ahh, thank you for the info! I didnt know about that.
But do you/someone know *why* there are few metabolites, no dietary restrictions? Does it bypass th liver and therefor does not get metabolized?Anyway, thanks for the info
Roland
poster:rod
thread:307271
URL: http://www.dr-bob.org/babble/20040127/msgs/307421.html