Posted by Kacy on February 20, 2004, at 11:06:47
In reply to Re: Buspar alone work for GAD for anyone?SSRI, posted by micro on February 20, 2004, at 0:40:57
I saw this on Scott's site:
Buspar
CYP-3A4 * azapirone:
5-HT1a full agonist (pre)
5-HT1a partial agonist (post)
DA2 partial agonist
* 1-PP metabolite:
NE-alpha2 antagonist
The drug's geneic name is Buspirone Hydrochloride. Does it have something to do with chloride and the sodium - potassium pump? Does anyone know what 1-PP metabolite means?I understand (I think) that an NE-alpha2 antagonist actually increases norepinephrine because the NE-alpha2 site is an inhibitor.
Is the 5-HT1a serotonin agonist working in the same vein as ssri's, or is that a subsite that does something else?
Thanks to anyone who can help.
poster:Kacy
thread:314724
URL: http://www.dr-bob.org/babble/20040218/msgs/316057.html