Posted by Althea8869 on February 29, 2004, at 18:15:06
In reply to Re: Wellbutrin Withdrawal » Althea8869, posted by Thereishope on February 29, 2004, at 15:22:50
The decision to choose clomipramine actually comes from a series of studies that show it to be far more effective than SSRI's in treating depression/dysthymia with melancholia/anhedonia.
Desipramine or Nortriptyline would be my second choices. These three seem to have the best side effect to efficacy ratios of the TCA's. I simply chose clomipramine because that was the one most of the studies chose to use. I still need to do some more research.Regarding your 'spaciness', im no doctor, but i'd probably put the wellbutrin at the top of the suspect list. Need to keep in mind, that of all the AD's out there, this is the one that has the medical community stumped it terms of how it works. I dont see many clinical studies with Wellbutrin in them, and I think its for precisely that reason. Ive been real lucky with side effects, other than some dry mouth for the first week, I havent noticed anything. We'll see what happens when I start tapering tomorrow.
Regarding your panic attacks, and I've had plenty - the real nasty ones too-, I dont know why you wouldnt just go with klonopin and use an AD as an AD. This stuff is an allstar. Most people can control anxiety/panic with as little as .5mg a day (once its had time to reach a 'true' steady state plasma concentration). Many criticize the use of klonopin, but I'll tell you what, I've had one panic attack in the last five years and I've never gone above .5mg/day and been as low as .25mg for more than a year. I think stories of getting off this stuff are a bit exaggerated. Though they may be taking much higher doses. Each time ive stopped for more than a few weeks, ive noticed some moderate withdrawl symptoms for the first 24-48 hours. After that, very minor.
I wish you the best of luck with whatever you try. Let me know which TCA you go with and how its working.
Take care.
poster:Althea8869
thread:318034
URL: http://www.dr-bob.org/babble/20040228/msgs/318806.html