Posted by ace on March 3, 2004, at 20:44:53
In reply to Nardil question: Ace, Mattdds, others please help!, posted by gardenergirl on March 3, 2004, at 13:48:53
> I have been on Nardil for atypical depression since Sept. I started at 45mg, which worked well for me except during a particularly extra stresful time. I upped it to 60 mg in late January.
>
> My main symptoms prior to tx: extreme difficulty getting out of bed. Alarm would go off, I would not get up. Would notice I was already late, would not get up. I think this is the "leaden paralysis" of atypical depression. I also would always be late, related to the above, but also difficulty keeping track of time. Last, I had terrible procrastination when it comes to writing tasks. As a student, all of these were a real problem.
>
> At 45mg, I experienced early awakening, usually around 5 or 5:30, sometimes as early as 4 am. I could never get back to sleep and usually felt pretty refreshed. This was good as it allowed me to get started on stuff and get to places on time. At 60mg this went away. I fully expected to go through a bit of insomnia when I upped it, but instead, my vegetative symptoms are returning. I am late again, I can't get out of bed, I am procrastinating out the wazoo.
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> Here's my question: what is causing this? Here are my hypotheses.
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> 1) Related to Nardil in some way. Better sleep cycle was actually insomnia and was a passing SE?
I believe the 'early awakening' was indeed a passing side effect.>
> 2)Nardil is pooping out.No, I don't think so...I think you need a higher dose of 75-90mg.
>
> 3)I missed two doses (15mg each)one day within the last few days. I have never done this before. Can it have such an effect?Very unlikely.
>
> 4)Therapy is stirring stuff up to the point that I am getting more depressed as I deal with the emotional stuff. This could be acting against the anti-vegetative effects of Nardil?Maybe. But when Nardil makes you feel good (at your optimum dose) I find it unlikely any exterior issues can shake its AD effect.
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> 5)I am working more on my dissertation, and set myself a deadline to have a complete draft. This is causing enough internal pressure to trigger another depressive episode despite the Nardil.Read above. When Nardil is acting 100%, I doubt any external factors can work against it.
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> 6)Weight gain from Nardil is making me depressed.Read above.
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> 7)I just do better on 45mg.I think you are passing through more side effects, and I believe ultimately you will need a higher dose....
>
> What do the rest of you think? Any other ideas? What should I do? Anyone else experinece something like this?I experienced the sleep phenomenon and also the vegetative sx in early therapy with Nardil. Time got rid of them...90mg created an unshakeble, breathtaking AD response.
Try 90mg...(after 4 weeks on 60mg)
>
> gg
poster:ace
thread:319742
URL: http://www.dr-bob.org/babble/20040228/msgs/319922.html