Posted by rod on March 6, 2004, at 5:22:00
In reply to Re: Dosage of Galantamine for non Alzheimer Purpose?, posted by SLS on March 4, 2004, at 7:25:36
> Although it doesn't affect everyone this way, Ach cholinesterase inhibitors like galantamine are known to cause or make worse depression. I would still try it, though.
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> - ScottYes, I know about this and have experienced this by myself. Exelon is quite depressiogenic for me, but Galantamine schould be somewhat different, because it directly or indirectly increases stimulation of nicotinic acetylcholine receptors. Thats a feature which isnt shared with any of the other achetylcholine-esterase inhibitors. I am asking because I feared the dangers of a cholinergic crisis. These drugs are lethal in overdose.
And hell yes, it seems to work for me! Its day 3 on 6 mg and I really feel an improvement in memory but whats most astonishing also in mood, mental energy, and improves my inability to make a decision. I think many of these improvements are also a result of incresaed perfusion (blood flow) of the brain (Thats what the AchE Inh. also do). And conincidentally I do have left brain sided hypoperfusion, which the doctors I have talked about are somewhat ignoring. The ability to make a decision is related to the left frontal lobe...
Hmmm, I think I will take it for long term use.
Other drugs I take are Lamictal, Neurontin, Solian (Amisulpride), Nortriptyline, Amantadine and Diphenhydramine.Roland
PS I hope this is not a transient effect.
poster:rod
thread:320016
URL: http://www.dr-bob.org/babble/20040304/msgs/321043.html