Posted by zeugma on March 6, 2004, at 12:55:06
In reply to Re: Anyone tried Reboxetine and STRATTERA?????????????, posted by King Vultan on March 6, 2004, at 12:09:54
Nortriptyline is somewhat sedating, especially when I combine it with buspirone. It was the combination of nortriptyline and buspirone that began to make a dent in my insomnia.
Nortriptyline by itself does sedate, but it's a little tricky, because it takes about 8 hours to reach peak plasma levels in the blood. The lower the dose, the earlier i had to take it to get a sedative effect. At 40-50 mg/day, I took it at 2 pm to be asleep by 12. At 60 mg/day, I could push it back to 4 pm. At 75 mg, I can take it at around 7:30 and be asleep by 11. All of this, however, occurs most reliably when potentiated by buspirone (otherwise I'm often up all night).
Buspirone gets the 'placebo' rap so often, and its ridiculously short half life means I have to take it bid, so i often 'forget' to take it, and wind up with insomnia, or really bad sleep quality.
poster:zeugma
thread:320967
URL: http://www.dr-bob.org/babble/20040304/msgs/321134.html