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Tolerance reversal.

Posted by Questionmark on March 7, 2004, at 7:56:08

Two more questions-- related to treatment of antidepressant poop-out:
1) How/why in the world are opioid antagonists (e.g. naltrexone) possibly beneficial for antidepressant poop-out? Wouldn't these just make one more dysphoric, regardless of whether or not s/he was on an antidepressant (opioid agonist or not)?? How in the world does this work?

2.a.) Which do you think would be best for antidepressant poop-out (and which for which types of antidepressants, if they differ on this): (A) Opioid antagonist, (B) NMDA antagonist, or (C) lithium?
2.b.) Why?
THANK YOU!

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poster:Questionmark thread:321526
URL: http://www.dr-bob.org/babble/20040304/msgs/321526.html