Posted by King Vultan on March 14, 2004, at 10:48:13
In reply to Trying Nardil?, posted by mark57 on March 14, 2004, at 8:43:14
> Hi, I've been taking Wellbutrin SR now for about 3 weeks. There's been no improvement with my depression. The only things I've noticed is more memory loss and being a lot more irritable/short tempered. I don't know if these side effects would eventually go away but I don't really want to wait and see. I'm thinking of trying Nardil now. I was on Parnate several months ago but didn't get much help, although my doc wouldn't let me increase the dosage over 60mg/day which I think might have helped. I've also been on a lot of the SSRIs without much help.
>
> Anyway now I'm wondering about trying Nardil. I have SAD as well as depression and have read that Nardil can be a great drug for this. My biggest concern is that Nardil will make me to drowsy. I understand that this can be one of its side effects. I already have a lot of trouble with that. I couldn't tolerate Xanax or Klonopin because I was falling asleep all the time. And I know you're not supposed to take stimulants with the MAOIs.
> Has anyone had positive experience taking Nardil when they also had fatigue/sleeping to much problems to start with.
>
> Thanks very much.
>
> Mark
>I'm currently on 45 mg/day Nardil, soon to be going up to 60 mg/day, and haven't noticed any excessive drowsiness, which I have noticed on drugs like Effexor and Strattera. However, there's not much doubt that Parnate is more activating than Nardil, as Parnate is essentially a stimulant with MAOI properties. I agree with your doctor in not going over 60 mg/day of the Parnate, as this would increase the risk of suffering a spontaneous hypertensive crisis IMO. From what I've read, Nardil is clearly more serotonergic than Parnate and is probably a better drug for social phobia.
I was on 300 mg/day Wellbutrin SR for a few months last year and also noticed an increase in irritability. It became so intolerable that I was forced to eventually discontinue the med. I did find the Wellbutrin to have some therapeutic effects and very few side effects other than the increased irritability. Parnate might be looked upon roughly as an extremely high powered version of Wellbutrin, as both are extremely dopaminergic. You might have better luck with something more serotonergic such as Nardil, or an SSRI, if you haven't already tried one (I'm assuming you have, though).
Todd
poster:King Vultan
thread:324196
URL: http://www.dr-bob.org/babble/20040313/msgs/324237.html