Posted by Lightshifter on March 24, 2004, at 20:37:33
I emailed this to Dr. Bob but I guess he can no longer get to reply to these directly. If anyone has any credible information on what happens when 2 drugs are given at the same time when they are both metabolized by the same enzyme (2d6) I'd appreciate a response... (Strattera and Nortryptaline are the 2 drugs being used at same time.)
Dear Dr. Bob,
I've been trying to get an answer to a question regarding the metabolizing of multiple drugs by the CYP450-2D6 enzyme.
Can you tell me if drug metabolism is decreased when multiple drugs are used that are metabolized by the same enzyme (2D6)? I have a friend who has been prescribed multiple drugs which are metabolized by it and was wondering if that may be reducing the metabolization and therefore the effectiveness of the drugs due to them competing for the same metabolizer.
I'd appreciate any help you might be able to provide and if you know of any links where this may be discussed I'd love to review the information.
Thanks For Your Help,
Dan Hunt
poster:Lightshifter
thread:327939
URL: http://www.dr-bob.org/babble/20040319/msgs/327939.html