Posted by rod on April 6, 2004, at 15:36:28
In reply to Re: effexor and ectasy -LINK -nytimes.com, posted by PsychoSage on April 5, 2004, at 19:17:47
> ..Both times were with meth..
Im sorry if this happened to you, but no one is talking amount meth here. The substance discussed here is MDMA not meth. No one said its "safe" with any other drug than MDMA. Any i agree to a certain extend, that an SSRI does not block the effect of MDMA for 100%. It just greatly decreases it. And someone who takes an SSRI can be close to serotonin syndrom by the SSRI alone. Serotonin Syndrome also accurs with SSRI monotherapy in some individulas. And if such a person, close to serotonin syndrom due to SSRI, takes MDMA, the reduced increase in serotonin might be enough to result in serotonin syndrome, in my opinion. Thats at least an psausible explanation and might fit some cases.
And the study http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12404538
demonstates the theoretical interaction of MDMA and citalopram, an SSRI. And these people were taking pharmaceutical grade MDMA.
> ..from her pill, and she was kind of pissed. Then she became incredibly ill with the classic serotonin syndrome symptoms.As I said, you never really know what you get. What did she thought to take? Also meth, or E?
> Effexor has been implicated in many serotonin toxicity cases with or without MDMA. MDMA has definitely been implicated in a lot of serotonin toxicity cases. If you take them together, I think they would kick your but.
As it has been said before: "serotonin increase by MDMA alone" + "Serotonin increase by SSRI alone" =! (does not equal) "Serotonin increase by SSRI and MDMA coadministered". Its "Serotonin increase by SSRI alone" + "a tiny bit more".
And your links *dont* mention anything about (SSRI or Effexor) + MDMA = Death
I think we have a tiny problem about comunication here...
Roland
poster:rod
thread:332813
URL: http://www.dr-bob.org/babble/20040402/msgs/333388.html