Posted by harryp on May 7, 2004, at 22:27:51
In reply to ok, here's what my pdoc said, posted by zeugma on May 7, 2004, at 21:21:06
On the whole, it sounds like you have a good doctor who takes you seriously.
He is right about norepinephrine being very active in the brainstem, but the brainstem doesn't really have much to do with mood (sleep/wake cycles--yes, which is certainly part of depressive pathology), as far as I know. I'm sure nortriptiline and desipramine also must operate on mood centers, or else they probably would be ineffective as AD's.
Sounds like your doc is open-minded, though. I hope these changes work for you!
(I'm looking at a current neuropharmacology text as I write this--it is fascinating, but the whole book could be summarized "we know little or nothing about how psychoactive drugs really work...")
You just have to keep trying something until you get results!
poster:harryp
thread:343353
URL: http://www.dr-bob.org/babble/20040505/msgs/344601.html