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Knowledgeable brothers and sisters in Nardil...

Posted by Questionmark on May 29, 2004, at 3:48:19

2 questions that i have yet to get answered:

1) Is there any truth to the suggestion that one should eventually lower his/her dose of Nardil to a "maintanence dose"? i've heard/read this so many times but based on personal experience, lowering the dose results in decreased effects very quickly (i.e., the next day or so). Because of this and how quickly i can feel withdrawal-like symptoms (that are reminiscent of Paxil withdrawal) after missing a full day's dose or so, or, say, two half- days' doses, i've also started to become really skeptical of the claim that Nardil's inhibition of MAO (or reduction of MAO enzymes at least) lasts for days or even weeks.
What say yous? What's the truth?

2) What is the physiological and/or pharmacological reason for it being preferable to split the Nardil dose to 2 or 3 times per day?
(Especially if that is true about MAO reduction/inhibition lasting for days or weeks-- about which, again, i now have my doubts). Is it just due to the GABA-increasing and (maybe) anticholinergic effects of Nardil? Please explain.

ThAAAAnk YoUUUsss.


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poster:Questionmark thread:351768
URL: http://www.dr-bob.org/babble/20040527/msgs/351768.html