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a note and reference

Posted by Chairman_MAO on June 2, 2004, at 19:30:50

In reply to Re: Stim to counter benzo cognition problems? » jaby, posted by Chairman_MAO on June 2, 2004, at 19:22:18

I believe that benzodiazepines decrease acetylcholine release. Acetylcholine, for the uninitiated, is vital for cognition. The galantamine helps compensate for decreased cholinergic activity.

Akush Ginekol (Sofiia). 1987;26(3):28-31.

[Attempt to eliminate residual somnolence and disorientation with nivaline after anesthesia with ketalar and diazepam for minor obstetrical and gynecologic surgery]

[Article in Bulgarian]

Chakalova E, Marinova M, Srebreva M, Anastasov D, Ploskov K.

PIP: Effectiveness of the anticholinergic agent nivaline to prevent side-effects of anesthetics ketalar and diazepam was studied in 40 pregnant women (15-40 years old) undergoing induced abortion during the 1st trimester. The patients were divided into two groups. Group 1 included 20 patients who received anesthesia with diazepam (10 mg) and ketalar (50-70 mg) alone. Group 2 included 20 patients undergoing anesthesia under diazepam-ketalar in combination with nivaline (10 mg, iv) during an early postoperative period. The degree of somnolence and disorientation was assessed immediately after anesthesia, and 5, 10, 15, 30 and 60 min after surgery using a scale of 1 to 4 (from response to verbal commands and pain stimulus to complete absence of response). The patients in group 2 were more alert than the patients in group 1 only 5, 10 and 15 min after surgery.

Neurosci Lett. 1989 Oct 23;105(1-2):195-9. Related Articles,Links


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