Posted by Chairman_MAO on June 9, 2004, at 19:06:09
In reply to Re: how is wellbutrin an AD, and Ritalin not » Keith Talent, posted by King Vultan on June 9, 2004, at 17:11:22
My position on Wellbutrin is identical to King Vultan's. I'd like to add, however, that in the original clinical investigations of bupropion as an antidepressant, the dosage range used was 450mg-900mg (or perhaps it was 600mg-900mg, I do not remember). Now, in the Wellbutrin monograph, they note that it has CNS stimulant effects at 400mg and above. Coincidence? I believe that, at doses of 450mg and above, Wellbutrin probably is a much more robust antidepressant because it's essentially a dysphoric stimulant. That is, it makes you feel crappy if you take "too much" instead of elated, as the "stimulants" often do. This highlights an important point: the predominant ethos among misguided biopsychiatrists is that an antidepressant should only be capable of making people in the deepest depths of unending clinical depression feel less terrible; it shouldn't be capable of actually elevating mood. This view deprives many depressives of the medication they need to actually feel well.
poster:Chairman_MAO
thread:354773
URL: http://www.dr-bob.org/babble/20040608/msgs/355219.html