Posted by rod on June 22, 2004, at 7:26:50
In reply to Re: Maprotiline / Oxaprotiline, metabol. or diff. drug » rod, posted by SLS on June 22, 2004, at 7:01:22
> > Does anybody know if Maprotiline gets metabolised into oxaprotiline, or are they 2 different drugs.
> > I didnt find an answer to this on the internet. So any info is much appreciated.
> >
> > thanks
> > Roland
>
>
> Hi Roland.
>
> I infer from these two Medline abstracts that the two drugs are both parent drugs of similar parallel metabolites. They don't seem to be metabolites of each other. I think Chemist would be able to interpret the literature more definitevely.
>
> What's up?
>
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3984384
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=6464500
>
>
> - ScottDear Scott,
Thanks for taking the time to look this up.
you are right, they seem to be different drugs. :(
I read some interesting things about oxaprotiline. It has an indirect effect on dopamine recepters and so on...
So I will have to deal with Maprotiline.Whats up with me?
Well, not doing so bad.And how are you?
Roland
poster:rod
thread:358903
URL: http://www.dr-bob.org/babble/20040621/msgs/358922.html