Re: FDA Finds Gepirone ER 'Not Approvable'

Posted by SLS on June 26, 2004, at 6:09:39

In reply to Re: FDA Finds Gepirone ER 'Not Approvable', posted by SLS on June 25, 2004, at 22:20:32

I neglected to mention that buspirone and gepirone are both metabolized to form 1-PP (1-(2-pyrimidinyl)-piperazine). 1-PP is a NE alpha-2 receptor antagonist like Remeron, only without the potent antihistaminic properties of Remeron. This is yet another rationale for the use of these drugs as augmentors of antidepressants.

- Scott

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FDA Finds Gepirone ER 'Not Approvable' jrbecker 6/25/04
Re: FDA Finds Gepirone ER 'Not Approvable' linkadge 6/25/04
The FDA is Hurting Consumers Shawn. T. 6/25/04
Re: FDA Finds Gepirone ER 'Not Approvable' SLS 6/25/04
Re: FDA Finds Gepirone ER 'Not Approvable' SLS 6/26/04
Re: FDA Finds Gepirone ER 'Not Approvable' » SLS jrbecker 6/27/04
Re: FDA Finds Gepirone ER 'Not Approvable' » jrbecker SLS 6/27/04
Re: FDA Finds Gepirone ER 'Not Approvable' zeugma 6/27/04
Re: FDA Finds Gepirone ER 'Not Approvable' jrbecker 6/28/04
Re: FDA Finds Gepirone ER 'Not Approvable' Cecilia 6/29/04

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