Posted by harryp on July 6, 2004, at 10:29:41
In reply to Re: this article scares me, posted by linkadge on July 5, 2004, at 16:52:13
Hi!
To be honest, most SSRI research is questionable.
I wouldn't worry too much about this. You simply can't draw those kinds of conclusions responsibly from one study. Furthermore, MAO is ubiquitous in the body (unless you are taking a MAOI) and amine oxidation must occur all the time in the brain. I'm a little suspicious of his claim that oxidation releases toxic compounds that destroy neurons (I think he means free-radicals, which can do damage, but those are a normal product in the body).
It's possible that inhibiting serotonergic reuptake would increase oxidation (by increasing the enzyme substrate) and yield more free radicals than usual--but basically we'd be seeing lots of brain-damaged people at this point if Prozac were as bad as he suggests.
poster:harryp
thread:363268
URL: http://www.dr-bob.org/babble/20040704/msgs/363452.html