Posted by iris2 on July 27, 2004, at 20:57:15
In reply to Re: Amisulpride,Mirapex,Requip...?, posted by SLS on July 27, 2004, at 20:50:20
> Hi Iris2.
>
> It will be interesting to see what suggestions some of the newer members in the community have to offer you.
>
> What was your experience with Effexor the very first time you tried it?
>
> I would be very interersted to know how you respond to milnacipran. If you decide to try it, please keep us informed of your progress with it.
>
> One drug that is not often mentioned here is sibutramine (Meridia). I know one pdoc in Princeton who swears by it. Sibutramine was originally developed as an antidepressant, but ended up being approved as an anti-obesity agent. It inhibits the reuptake of both 5-HT and NE, and exhibits properties in rat brain in vivo suggesting DA reuptake inhibition and/or release as well, most likely the result of its metabolites. A drug company was recently developing one of the enantiomers, r-sibutramine, specifically as an antidepressant. Unfortunately, it ran out of money for the project.
>
> I have sibutramine on my list of things to try. I probably would have tried it by now if my medical insurance were to have paid for it. Meanwhile, I am waiting for Cymbalta to be approved. I'm sure you are already aware that this dual action SNRI (serotonin-norepinephrine reuptake inhibitor) antidepressant is to be decided upon by the FDA for approval in late September.
>
> Have you ever tried adding a mood stabilizer?
>
>
> - ScottScott,
The first time IS tried effexor I thought it had the potential to work well. I started to be calmer ( less anxious) yet felt energetic. Unfortunately I am unable to take it because of a bladder desease Intersticial cystitis. I have thought for a long time this would be a great med for me. I tried it several more times to see if I could tolerate a small amount even but it was very painful.
I think I looked into Meridia once and I might have tried it. I will have to look it up again and see what iS remember.
Do you have any suggestions to try ?
thanks,
iris2
poster:iris2
thread:371386
URL: http://www.dr-bob.org/babble/20040724/msgs/371400.html