Posted by Ame Sans Vie on August 22, 2004, at 6:18:17
In reply to The Truth about Stimulant Tolerance, posted by Philidor on August 21, 2004, at 19:51:35
Don't get your panties all in a bunch just because some people have done their research and found something that *does* work to prevent (or at least delay) stimulant tolerance. My guess is that you haven't done your research into this, nor have you tried the currently studied treatments available, or else you wouldn't be quite so unnecessarily bitter.
As far as your assertion that if stimulant tolerance prevention/reversal were possible then it'd be breaking news, then obviously you're not aware of the power the pharmaceutical industry holds, nor the fact that it takes ten or fifteen years for almost any new pharmaceutical development to see the light of day. Prozac (well, fluoxetine at least) has been around since the 70's... Cymbalta since the late 80's. Yet the discussion of the latter never appeared on these message boards until just a few years ago.
Dextromethorphan is about to be available (or perhaps already is?) in a formulation with morphine called 'Morphidex' which has been proven to both prevent and reverse morphine tolerance. By the same (plus additional) mechanisms, dextromethorphan and many other NMDA antagonists provide the same benefit for stimulant tolerance.
~Michael
(14 months using Adderall for depression with NO development of tolerance to euphorigenic or antianergic effects, thanks to DXM)
poster:Ame Sans Vie
thread:380561
URL: http://www.dr-bob.org/babble/20040821/msgs/380721.html