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Opposing pdoc views re: wellbutrin and seizures

Posted by Racer on August 25, 2004, at 13:15:50

This is pretty much just an academic question, but it's been on my mind, so I'm asking the people who might know from the inside:

Three doctors, three views on Wellbutrin's seizure risk.

Dr One: involuntarily hospitalized after S/A, said Wellbutrin was safe for someone with a history of eating disorders -- as long as the ED wasn't active. She prescribed it at a starting dose, which wasn't up to the therapeutic dose range but seemed to be starting to help when...

Dr Two: (Dr EyeCandy for anyone who's keeping score) *immediately* stopped it, said he had had too many patients experience seizures from it to risk it -- although, he wasn't concerned with any ED history, this was based solely on a skull fracture at the age of five -- and had very, very round eyes at the very thought of the danger. He did say, though, that the dosage was a factor: that his patients at doses over 400mg were 'something like ten times more likely' to experience seizures, but I've got a history of needing very high dosages to respond to any drug other than anti-biotics.

Dr Three: (initial eval yesterday, no *name* yet) said Dr EyeCandy was being *incredibly* overcautious: that Wellbutrin can be perfectly safe, at almost any dosage, for most people with a history of head trauma, and that the ED connection really is only related to purging behavior. He offered me three choices of meds to pick from, one of them was Wellbutrin. He told me the reasons he really didn't think it was the best choice for me, all of which sounded very reasonable and very valid to me, but said he would feel perfectly safe prescribing it to me, despite the history of (multiple) head traumas and the history of (and current) ED.

Yeah, yeah, I'm being much too suspicious of all the doctors say these days -- but I come by it honestly.

This question really ain't keeping me up nights, we did choose the new doc's first choice for me, but it did make me very curious to know what people here had experienced on this topic?

(Warning: I very nearly caught myself typing something like, "Are you now, or have you ever been..." Save us all from any attempt on my part to be funny today -- if you know something that might apply, all input very gratefully anticipated...)


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poster:Racer thread:382172
URL: http://www.dr-bob.org/babble/20040825/msgs/382172.html