N-methyl d-Aspartate Methylphenidate [Ritalin]

Posted by aazospiro on September 8, 2004, at 20:36:52

NMDA receptor antagonist disrupts acute and chronic effects of methylphenidate.

Interesting Stuff...for ADD'ers and stimulants Tolerance. Read more @http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11134695&itool=iconabstr
ADDITIONALLY & Interestingly, The cough suppressant dextromethorphan is an NMDA antagonist at least in low doses i.e. < 15 mg
and maybe of some value in preventing stimulant tolerance before it has occurred. hmmmmmmm!
I think memantine is also an NMDA antagonist. Also Valproate might have some value in prevent longterm stimulant tolerance resulting in lower maintenance doses.

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N-methyl d-Aspartate Methylphenidate [Ritalin] aazospiro 9/8/04
RE:RITALIN-DOES DMX PREVENT TOLERANCE. AME? paulbwell 9/10/04
RE:RITALIN-DOES DMX PREVENT TOLERANCE. AME? Philidor 9/13/04

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